The active ingredient in Nurofen: Ibuprofen

When the body picks up an infection, sustains an injury, or has both, the inflammatory response kicks in.  The inflammatory response produces chemicals called prostaglandins, which can make nearby nerves sensitive to pain. The pain response is important, as it helps our bodies realise that something is wrong. While this response may serve as a warning system, it can also make tissues inflamed, swollen and painful. Prostaglandins are one of the reasons why you may feel a sore throat when sick, or experience swelling with a sprained ankle. Nurofen’s main active ingredient is ibuprofen, which is a non-steroidal anti-inflammatory drug (NSAID) – also called an anti-inflammatory. Ibuprofen helps relieve pain and inflammation by blocking prostaglandin production.  Interestingly, not all pain relievers work in the same way. For instance, paracetamol which is a different pain reliever, is understood to help relieve pain by interrupting pain signals in the brain (central nervous system).

How Nurofen helps relieve fever

Fever or ‘having a high temperature’ is when the core temperature in our body rises higher than normal. You probably have a fever if your temperature is 38°C or higher.  Some of the effects associated with fever can include sweating, shivering, chills or aching muscles and joints. Whilst fever is commonly brought upon by infection, it can also occur for other reasons, such as underlying medical conditions. Fever is triggered when the immune system signals the brain, or more specifically the hypothalamus, which is our temperature control centre in the brain. Our hypothalamus is a bit like the body’s thermostat, controlling heat production and heat loss to maintain the ‘normal’ body temperature. In the case of fever, the immune system triggers the production of chemicals, including prostaglandins, which then raise the set point of the hypothalamus, resulting in an increase in body temperature. Nurofen can help reduce fever as ibuprofen blocks prostaglandin production.  If you or a family member is experiencing fever, you should consult your doctor or pharmacist for treatment advice.

How to take Nurofen

Adults and children over 12 years can take 2 standard Nurofen tablets (ibuprofen 200mg per tablet) initially, then 1–2 tablets every 4 to 6 hours when necessary, up to a maximum of 6 tablets in 24 hours. Children aged between 7–12 years can take 1 standard Nurofen tablet every 6 to 8 hours when necessary, up to a maximum of 4 tablets in 24 hours. The Nurofen for Children oral suspension range is suitable for children between the ages of 3 months to 12 years and the dosage is based on weight. Nurofen for Children can be administered every 6 to 8 hours when necessary. Nurofen should not be given to infants under 3 months of age.

Can I take Nurofen?

Nurofen, with its active ingredient ibuprofen, is an over-the-counter medication which can be used for temporary relief of pain and inflammation. Nurofen has products suitable from ages three months up to adults. However, it may not be suitable for some people, and you should always read the label to determine if the product is suitable for you.

Some medicines may not be right for you so always read the label before purchase and follow the directions for use. If you use medicines incorrectly, they can harm you. If your symptoms persist, talk to your health professional.

This article is for general information only and not intended as a substitute for medical advice. All information presented on these web pages is not meant to diagnose or prescribe. In all health-related matters, always consult your health professional.

Always read the label and follow the directions of use. Incorrect use could be harmful. If symptoms persist, talk to your healthcare professional.

NUROFEN® is a registered trademark of the Reckitt Benckiser Group of Companies. Level 47, 680 George St, Sydney 2000, NSW Australia. Prepared December 2024. RKT-M-33894.